Więcej pomysłów od użytkownika Marysia
"Parkinson’s Disease can occur through both genetic mutation and exposure to environmental and neurotoxins, the latter which causes mitochondrial oxidative stress and release of reactive oxygen species, leading to a number of cellular responses including apoptosis and the misfolding of α-synuclein, which can aggregate with itself and other proteins to form cytotoxic Lewy Bodies. Misfolded α-synuclein is normally ubiquitinated by parkin resulting in proteosomal degradation."

"Parkinson’s Disease can occur through both genetic mutation and exposure to environmental and neurotoxins, the latter which causes mitochondrial oxidative stress and release of reactive oxygen species, leading to a number of cellular responses including apoptosis and the misfolding of α-synuclein, which can aggregate with itself and other proteins to form cytotoxic Lewy Bodies. Misfolded α-synuclein is normally ubiquitinated by parkin resulting in proteosomal degradation."