Learn more about enzyme active site and substrate specificity in the Boundless open textbook. Enzymes catalyze chemical reactions by lowering activation energy barriers and converting substrate molecules to products.
Scraps From A Broad: Pocket Letter from Sandra in The Netherlands
Diagram depicting antibiotic resistance through alteration of the antibiotic's target site, modeled after MRSA's resistance to penicillin. Beta-lactam antibiotics permanently inactivate PBP enzymes, which are essential for bacterial life, by permanently binding to their active sites. MRSA, however, expresses a PBP that does not allow the antibiotic into its active site.
Catalysts are of paramount importance to achieve high efficiency and economic profit for most heterogeneous reactions. Since catalytic reaction occurs only when reactants reach the active sites, these active sites must be .
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2008 - Full text PDF - Novel mutations of the GLA gene in Japanese patients with Fabry disease and their functional characterization by active site specific chaperone - Shimotori - 2008 - Human Mutation - Wiley Online Library