I applied this twice a day- once in the morning and once at night. For the first 2 weeks, my skin still got some red bumps or pimples. After 3 weeks, I got what felt like a rash on my butt. I continued my regime through it, the rash went away after a few days, and on week 4 my rear was smooth, clear, no rash, no bumps and pimples at all and I cannot believe how great my skin looks and feels now. I use this once at night for maintenance.